Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia

Abera Ademasu; Bizuayehu Kerisew; Endalkachew Nibret; Abayneh Munshea; Melaku Adal

doi:doi:10.11648/j.ijnfs.20140304.22

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Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia

Abera Ademasu, Bizuayehu Kerisew, Endalkachew Nibret, Abayneh Munshea, Melaku Adal

Published in International Journal of Nutrition and Food Sciences (Volume 3, Issue 4)

Received: 3 July 2014 Accepted: 16 July 2014 Published: 30 July 2014

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Abstract

Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.

Published in	International Journal of Nutrition and Food Sciences (Volume 3, Issue 4)
DOI	10.11648/j.ijnfs.20140304.22
Page(s)	311-317
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Antiretroviral Therapy, Bahir Dar, HIV/AIDS, Serum Zinc Deficiency

References

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APA Style

Abera Ademasu, Bizuayehu Kerisew, Endalkachew Nibret, Abayneh Munshea, Melaku Adal. (2014). Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. International Journal of Nutrition and Food Sciences, 3(4), 311-317. https://doi.org/10.11648/j.ijnfs.20140304.22

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ACS Style

Abera Ademasu; Bizuayehu Kerisew; Endalkachew Nibret; Abayneh Munshea; Melaku Adal. Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. Int. J. Nutr. Food Sci. 2014, 3(4), 311-317. doi: 10.11648/j.ijnfs.20140304.22

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AMA Style

Abera Ademasu, Bizuayehu Kerisew, Endalkachew Nibret, Abayneh Munshea, Melaku Adal. Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. Int J Nutr Food Sci. 2014;3(4):311-317. doi: 10.11648/j.ijnfs.20140304.22

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@article{10.11648/j.ijnfs.20140304.22,
  author = {Abera Ademasu and Bizuayehu Kerisew and Endalkachew Nibret and Abayneh Munshea and Melaku Adal},
  title = {Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {3},
  number = {4},
  pages = {311-317},
  doi = {10.11648/j.ijnfs.20140304.22},
  url = {https://doi.org/10.11648/j.ijnfs.20140304.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20140304.22},
  abstract = {Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.},
 year = {2014}
}

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TY  - JOUR
T1  - Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia
AU  - Abera Ademasu
AU  - Bizuayehu Kerisew
AU  - Endalkachew Nibret
AU  - Abayneh Munshea
AU  - Melaku Adal
Y1  - 2014/07/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ijnfs.20140304.22
DO  - 10.11648/j.ijnfs.20140304.22
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 311
EP  - 317
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20140304.22
AB  - Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.
VL  - 3
IS  - 4
ER  -

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Author Information

Abera Ademasu

Bahir Dar Health Science College, department of Medical laboratory Technology, Bahir Dar, Ethiopia
Bizuayehu Kerisew

University of Bahir Dar, College of Science, department of Biology, Bahir Dar, Ethiopia
Endalkachew Nibret

University of Bahir Dar, College of Science, department of Biology, Bahir Dar, Ethiopia
Abayneh Munshea

University of Bahir Dar, College of Science, department of Biology, Bahir Dar, Ethiopia
Melaku Adal

University of Bahir Dar, College of Science, department of Biology, Bahir Dar, Ethiopia

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Abera Ademasu, Bizuayehu Kerisew, Endalkachew Nibret, Abayneh Munshea, Melaku Adal. (2014). Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. International Journal of Nutrition and Food Sciences, 3(4), 311-317. https://doi.org/10.11648/j.ijnfs.20140304.22

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ACS Style

Abera Ademasu; Bizuayehu Kerisew; Endalkachew Nibret; Abayneh Munshea; Melaku Adal. Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. Int. J. Nutr. Food Sci. 2014, 3(4), 311-317. doi: 10.11648/j.ijnfs.20140304.22

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AMA Style

Abera Ademasu, Bizuayehu Kerisew, Endalkachew Nibret, Abayneh Munshea, Melaku Adal. Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia. Int J Nutr Food Sci. 2014;3(4):311-317. doi: 10.11648/j.ijnfs.20140304.22

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@article{10.11648/j.ijnfs.20140304.22,
  author = {Abera Ademasu and Bizuayehu Kerisew and Endalkachew Nibret and Abayneh Munshea and Melaku Adal},
  title = {Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {3},
  number = {4},
  pages = {311-317},
  doi = {10.11648/j.ijnfs.20140304.22},
  url = {https://doi.org/10.11648/j.ijnfs.20140304.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20140304.22},
  abstract = {Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.},
 year = {2014}
}

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TY  - JOUR
T1  - Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia
AU  - Abera Ademasu
AU  - Bizuayehu Kerisew
AU  - Endalkachew Nibret
AU  - Abayneh Munshea
AU  - Melaku Adal
Y1  - 2014/07/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ijnfs.20140304.22
DO  - 10.11648/j.ijnfs.20140304.22
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 311
EP  - 317
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20140304.22
AB  - Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.
VL  - 3
IS  - 4
ER  -

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