Bezold Jarisch reflex (BJR) is an eponym for a triad of responses namely: bradycardia, hypotension and vasodilation that develops upon stimulation of intracardiac mechanoreceptors and is mediated by vagal afferent nerve fibers. Though it was first reported in 1867 it remains a topic of discussion due to its implications in various clinical scenarios. The reflex can be stimulated either by mechanical or chemical stimulators. Often considered a physiologic response, if identified by the clinician at earlier phase, can avoid cardiac complication, it also acts as a prognostic indicator in various diseases. This review focuses on the physiology of the BJR and its possible physiologic role in several clinical situations. We used evidence obtained from a computerized literature of medical databases search using PubMed/Medline/NIH (all articles till October 2019). The search was carried out with MeSH phrase “Bezold Jarisch reflex” and articles were limited to English language only. The relevant published reports, abstracts and human studies with clinical cases to determine the clinical implications of BJR were considered for the review. It has been concluded that BJR is a physiologic response that can occur in number of clinical scenarios. Therefore, simultaneous occurrence of bradycardia and hypotension should alert clinicians to the possibility of BJR.
| Published in | American Journal of Internal Medicine (Volume 8, Issue 1) |
| DOI | 10.11648/j.ajim.20200801.15 |
| Page(s) | 24-29 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Bezold Jarisch Reflex, C-fibers, Chemoreceptors, Myocardial Receptors
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APA Style
Sanjeev Arya, Shantanu Belwal, Bhupesh Uniyal, Bhuwan Tiwari, Preeti Sharma. (2020). Bezold Jarisch Reflex- New Interest, Old Phenomenon. American Journal of Internal Medicine, 8(1), 24-29. https://doi.org/10.11648/j.ajim.20200801.15
ACS Style
Sanjeev Arya; Shantanu Belwal; Bhupesh Uniyal; Bhuwan Tiwari; Preeti Sharma. Bezold Jarisch Reflex- New Interest, Old Phenomenon. Am. J. Intern. Med. 2020, 8(1), 24-29. doi: 10.11648/j.ajim.20200801.15
AMA Style
Sanjeev Arya, Shantanu Belwal, Bhupesh Uniyal, Bhuwan Tiwari, Preeti Sharma. Bezold Jarisch Reflex- New Interest, Old Phenomenon. Am J Intern Med. 2020;8(1):24-29. doi: 10.11648/j.ajim.20200801.15
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Download@article{10.11648/j.ajim.20200801.15,
author = {Sanjeev Arya and Shantanu Belwal and Bhupesh Uniyal and Bhuwan Tiwari and Preeti Sharma},
title = {Bezold Jarisch Reflex- New Interest, Old Phenomenon},
journal = {American Journal of Internal Medicine},
volume = {8},
number = {1},
pages = {24-29},
doi = {10.11648/j.ajim.20200801.15},
url = {https://doi.org/10.11648/j.ajim.20200801.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200801.15},
abstract = {Bezold Jarisch reflex (BJR) is an eponym for a triad of responses namely: bradycardia, hypotension and vasodilation that develops upon stimulation of intracardiac mechanoreceptors and is mediated by vagal afferent nerve fibers. Though it was first reported in 1867 it remains a topic of discussion due to its implications in various clinical scenarios. The reflex can be stimulated either by mechanical or chemical stimulators. Often considered a physiologic response, if identified by the clinician at earlier phase, can avoid cardiac complication, it also acts as a prognostic indicator in various diseases. This review focuses on the physiology of the BJR and its possible physiologic role in several clinical situations. We used evidence obtained from a computerized literature of medical databases search using PubMed/Medline/NIH (all articles till October 2019). The search was carried out with MeSH phrase “Bezold Jarisch reflex” and articles were limited to English language only. The relevant published reports, abstracts and human studies with clinical cases to determine the clinical implications of BJR were considered for the review. It has been concluded that BJR is a physiologic response that can occur in number of clinical scenarios. Therefore, simultaneous occurrence of bradycardia and hypotension should alert clinicians to the possibility of BJR.},
year = {2020}
}
TY - JOUR T1 - Bezold Jarisch Reflex- New Interest, Old Phenomenon AU - Sanjeev Arya AU - Shantanu Belwal AU - Bhupesh Uniyal AU - Bhuwan Tiwari AU - Preeti Sharma Y1 - 2020/01/16 PY - 2020 N1 - https://doi.org/10.11648/j.ajim.20200801.15 DO - 10.11648/j.ajim.20200801.15 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 24 EP - 29 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20200801.15 AB - Bezold Jarisch reflex (BJR) is an eponym for a triad of responses namely: bradycardia, hypotension and vasodilation that develops upon stimulation of intracardiac mechanoreceptors and is mediated by vagal afferent nerve fibers. Though it was first reported in 1867 it remains a topic of discussion due to its implications in various clinical scenarios. The reflex can be stimulated either by mechanical or chemical stimulators. Often considered a physiologic response, if identified by the clinician at earlier phase, can avoid cardiac complication, it also acts as a prognostic indicator in various diseases. This review focuses on the physiology of the BJR and its possible physiologic role in several clinical situations. We used evidence obtained from a computerized literature of medical databases search using PubMed/Medline/NIH (all articles till October 2019). The search was carried out with MeSH phrase “Bezold Jarisch reflex” and articles were limited to English language only. The relevant published reports, abstracts and human studies with clinical cases to determine the clinical implications of BJR were considered for the review. It has been concluded that BJR is a physiologic response that can occur in number of clinical scenarios. Therefore, simultaneous occurrence of bradycardia and hypotension should alert clinicians to the possibility of BJR. VL - 8 IS - 1 ER -
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