Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma

Yurii Feshchenko; Liudmyla Iashyna; Svitlana Opimakh; Maryna Polianska; Viktoria Ignatieva; Svitlana Moskalenko; Galyna Gumenuk; Inna Zvol; Nataliia Vlasova; Liudmyla Halai

doi:doi:10.11648/j.ajim.20200801.13

Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma

Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, Svitlana Moskalenko, Galyna Gumenuk, Inna Zvol, Nataliia Vlasova, Liudmyla Halai

Published in American Journal of Internal Medicine (Volume 8, Issue 1)

Received: 16 December 2019 Accepted: 3 January 2020 Published: 13 January 2020

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Abstract

Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.

Published in	American Journal of Internal Medicine (Volume 8, Issue 1) This article belongs to the Special Issue New Approaches to Manage Difficult-to-Control, Severe Asthma
DOI	10.11648/j.ajim.20200801.13
Page(s)	14-18
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Bronchial Asthma, Lung Ventilation, Alveolar Ventilation

References

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APA Style

Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, et al. (2020). Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. American Journal of Internal Medicine, 8(1), 14-18. https://doi.org/10.11648/j.ajim.20200801.13

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ACS Style

Yurii Feshchenko; Liudmyla Iashyna; Svitlana Opimakh; Maryna Polianska; Viktoria Ignatieva, et al. Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. Am. J. Intern. Med. 2020, 8(1), 14-18. doi: 10.11648/j.ajim.20200801.13

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AMA Style

Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, et al. Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. Am J Intern Med. 2020;8(1):14-18. doi: 10.11648/j.ajim.20200801.13

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@article{10.11648/j.ajim.20200801.13,
  author = {Yurii Feshchenko and Liudmyla Iashyna and Svitlana Opimakh and Maryna Polianska and Viktoria Ignatieva and Svitlana Moskalenko and Galyna Gumenuk and Inna Zvol and Nataliia Vlasova and Liudmyla Halai},
  title = {Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {1},
  pages = {14-18},
  doi = {10.11648/j.ajim.20200801.13},
  url = {https://doi.org/10.11648/j.ajim.20200801.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200801.13},
  abstract = {Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.},
 year = {2020}
}

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TY  - JOUR
T1  - Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma
AU  - Yurii Feshchenko
AU  - Liudmyla Iashyna
AU  - Svitlana Opimakh
AU  - Maryna Polianska
AU  - Viktoria Ignatieva
AU  - Svitlana Moskalenko
AU  - Galyna Gumenuk
AU  - Inna Zvol
AU  - Nataliia Vlasova
AU  - Liudmyla Halai
Y1  - 2020/01/13
PY  - 2020
N1  - https://doi.org/10.11648/j.ajim.20200801.13
DO  - 10.11648/j.ajim.20200801.13
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 14
EP  - 18
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200801.13
AB  - Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.
VL  - 8
IS  - 1
ER  -

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Author Information

Yurii Feshchenko

Department of Pulmonology, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Liudmyla Iashyna

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Svitlana Opimakh

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Maryna Polianska

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Viktoria Ignatieva

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Svitlana Moskalenko

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Galyna Gumenuk

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Inna Zvol

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Nataliia Vlasova

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Liudmyla Halai

Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine

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APA Style

Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, et al. (2020). Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. American Journal of Internal Medicine, 8(1), 14-18. https://doi.org/10.11648/j.ajim.20200801.13

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ACS Style

Yurii Feshchenko; Liudmyla Iashyna; Svitlana Opimakh; Maryna Polianska; Viktoria Ignatieva, et al. Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. Am. J. Intern. Med. 2020, 8(1), 14-18. doi: 10.11648/j.ajim.20200801.13

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AMA Style

Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, et al. Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma. Am J Intern Med. 2020;8(1):14-18. doi: 10.11648/j.ajim.20200801.13

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@article{10.11648/j.ajim.20200801.13,
  author = {Yurii Feshchenko and Liudmyla Iashyna and Svitlana Opimakh and Maryna Polianska and Viktoria Ignatieva and Svitlana Moskalenko and Galyna Gumenuk and Inna Zvol and Nataliia Vlasova and Liudmyla Halai},
  title = {Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {1},
  pages = {14-18},
  doi = {10.11648/j.ajim.20200801.13},
  url = {https://doi.org/10.11648/j.ajim.20200801.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200801.13},
  abstract = {Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma
AU  - Yurii Feshchenko
AU  - Liudmyla Iashyna
AU  - Svitlana Opimakh
AU  - Maryna Polianska
AU  - Viktoria Ignatieva
AU  - Svitlana Moskalenko
AU  - Galyna Gumenuk
AU  - Inna Zvol
AU  - Nataliia Vlasova
AU  - Liudmyla Halai
Y1  - 2020/01/13
PY  - 2020
N1  - https://doi.org/10.11648/j.ajim.20200801.13
DO  - 10.11648/j.ajim.20200801.13
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 14
EP  - 18
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200801.13
AB  - Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.
VL  - 8
IS  - 1
ER  -

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