Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India

Nazish Fatima; Abida Malik; Parvez Anwar Khan; Sana Ali; Haris Manzoor Khan; Nabeela

doi:doi:10.11648/j.ajim.20140201.12

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Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India

Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, Nabeela

Published in American Journal of Internal Medicine (Volume 2, Issue 1)

Received: 29 December 2013 Published: 20 February 2014

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Abstract

Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.

Published in	American Journal of Internal Medicine (Volume 2, Issue 1)
DOI	10.11648/j.ajim.20140201.12
Page(s)	6-9
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Syphilis, VDRL, TPHA, HIV, ANC

References

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Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. (2014). Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. American Journal of Internal Medicine, 2(1), 6-9. https://doi.org/10.11648/j.ajim.20140201.12

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ACS Style

Nazish Fatima; Abida Malik; Parvez Anwar Khan; Sana Ali; Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am. J. Intern. Med. 2014, 2(1), 6-9. doi: 10.11648/j.ajim.20140201.12

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AMA Style

Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am J Intern Med. 2014;2(1):6-9. doi: 10.11648/j.ajim.20140201.12

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@article{10.11648/j.ajim.20140201.12,
  author = {Nazish Fatima and Abida Malik and Parvez Anwar Khan and Sana Ali and Haris Manzoor Khan and Nabeela},
  title = {Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India},
  journal = {American Journal of Internal Medicine},
  volume = {2},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.ajim.20140201.12},
  url = {https://doi.org/10.11648/j.ajim.20140201.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140201.12},
  abstract = {Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.},
 year = {2014}
}

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TY  - JOUR
T1  - Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India
AU  - Nazish Fatima
AU  - Abida Malik
AU  - Parvez Anwar Khan
AU  - Sana Ali
AU  - Haris Manzoor Khan
AU  - Nabeela
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajim.20140201.12
DO  - 10.11648/j.ajim.20140201.12
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20140201.12
AB  - Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.
VL  - 2
IS  - 1
ER  -

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Author Information

Nazish Fatima

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Abida Malik

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Parvez Anwar Khan

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Sana Ali

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Haris Manzoor Khan

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Nabeela

Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

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Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. (2014). Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. American Journal of Internal Medicine, 2(1), 6-9. https://doi.org/10.11648/j.ajim.20140201.12

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ACS Style

Nazish Fatima; Abida Malik; Parvez Anwar Khan; Sana Ali; Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am. J. Intern. Med. 2014, 2(1), 6-9. doi: 10.11648/j.ajim.20140201.12

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AMA Style

Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, et al. Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India. Am J Intern Med. 2014;2(1):6-9. doi: 10.11648/j.ajim.20140201.12

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@article{10.11648/j.ajim.20140201.12,
  author = {Nazish Fatima and Abida Malik and Parvez Anwar Khan and Sana Ali and Haris Manzoor Khan and Nabeela},
  title = {Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India},
  journal = {American Journal of Internal Medicine},
  volume = {2},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.ajim.20140201.12},
  url = {https://doi.org/10.11648/j.ajim.20140201.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140201.12},
  abstract = {Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.},
 year = {2014}
}

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TY  - JOUR
T1  - Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India
AU  - Nazish Fatima
AU  - Abida Malik
AU  - Parvez Anwar Khan
AU  - Sana Ali
AU  - Haris Manzoor Khan
AU  - Nabeela
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajim.20140201.12
DO  - 10.11648/j.ajim.20140201.12
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20140201.12
AB  - Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.
VL  - 2
IS  - 1
ER  -

Copy | Download